Manchester United suffered a heavy blow in the opening game! Amorin confirmed that the two defenders were absent, and whether Onana could play is doubtful

Manchester United will host Arsenal at home in Sunday's Premier League opening match, but the Red Devils may have four key players unable to play.

Ruben Amorin confirmed that both Lisandro Martinez and Nussel Mazravie will miss Manchester United's Premier League opening match against Arsenal. On Sunday, the Red Devils will welcome the Gunners at Old Trafford and embark on the 2025-26 season.

In view of Manchester United's poor performance last season, Amorin is eager to have a good start to the new season. But his team will play against Mikel Arteta's team in the absence of two core defenders.

Martinez is still recovering due to a long-term knee injury and will miss the game; Mazravie is absent due to a hamstring strain. However, Amorin confirmed that Andre Onana and Joshua Zilkize could both play.

At the pre-match press conference, Amorin said: "No, Licha (Lisandro Martinez) and Mazlawi can't play this game. Josh (Zilkeze) and Andre (Onana) are recovering and may play. Let's see what the situation is."

Except for these four, all other Manchester United players remain healthy. Manchester United, under Amorin, has a difficult start to the new season and will face Arsenal, Manchester City and Chelsea 10 months ago. When asked about the goal of the new season, Amorin responded: "It's hard to tell."

"We can't change everything in four weeks, but the team is indeed improving. We train harder and are more prepared to deal with the high intensity of the game. It's obvious that I'm more confident now. Step by step, we will become a better team."

Amorin added: "We want to return to the European game. We must be realistic with the fans - we have to put in great efforts because many teams have been running-in longer than we do. We have to focus on playing games one by one and want to win against Arsenal."

Amorin also said that after learning a lot from the club's dilemma last year, he is now more capable of dealing with the challenge of Old Trafford. He said: "I learned a lot last season. I don't need to focus on the future, that doesn't matter, and I don't care. What I have to do is live every day with my feet on the ground. I will block all the noise that may interfere with the team and prepare for the game against Arsenal." After

against Arsenal, Manchester United will challenge Fulham away next weekend, and then they will play against Grimsby Town in the second round of the League Cup draw on Wednesday.